This neuropeptide, also called corticotrophin releasing factor CRFis a key mediator of the stress response [ 26 ].
The term CRH is used when describing its function in the neuroendocrine system and the term CRF is commonly used when describing its function as a neurotransmitter. Two out of three patients presenting to emergency, inpatient or outpatient mental health services have experienced childhood physical or sexual abuse Read et al.
When our stress response becomes over-activated in childhood, it changes the functioning of the stress response. Adversity in childhood can include experiences such as emotional, physical, and sexual abuse, neglect, and the sudden loss of a parent or caregiver.
Beliefs about themselves, others, and the world diminish their sense of competency. Exposure to early life adversity increases anxiety and depressive behaviours in rodents, which endures well into adulthood. It helped me find answers to help my wife whom I love dearly, who walked out on a twenty year marriage and four children because her past abuse was coming up.
So, getting your own ACE score —that is the first step in the right direction. Individuals with childhood trauma show much more depression, anxiety, distorted cognition, personality deficits, and lower levels of social support, which may represent the social and psychological vulnerability for developing psychiatric disorders after childhood trauma experiences.